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However, APR-246 also has p53-independent function via MQ binding to thioredoxin reductase and glutathione, leading to depletion of glutathione and accumulation of reactive oxygen species (ROS), which can feed forward p53 activation (Figure 1).1918 Indeed, the authors also show synergy in TP53 knockout mutant cell lines where there is absence of p53, albeit with less synergy than in the missense mutant model

With regular supplementation, you can strengthen your immune response and improve overall health

When levels are low, the body's ability to rebuild and maintain tissues can be compromised leading to slower recovery from injuries, surgeries, or illnesses

Then again, anything over 0 was an improvement, ha